Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | BCL3 | P20749 | 5/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.48 |
| ▸ | KIT | P10721 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035287 | 0.93 | BCL3 (0.59) | KMT2ABCL3PDGFRBKITKDR | |
| SCHEMBL6035311 | 0.93 | KMT2A (0.49) | KMT2APDGFRBKITKDRALDH1A1 | |
| SCHEMBL6035306 | 0.91 | CYP1A2 (0.48) | KMT2ABCL3PDGFRBKITKDR | |
| SCHEMBL6035719 | 0.87 | BCL3 (0.55) | KMT2ABCL3ALDH1A1POLB | |
| SCHEMBL6035410 | 0.87 | MKNK2 (0.45) | KMT2APDGFRBKITKDR | |
| SCHEMBL7804383 | 0.86 | KMT2A (0.46) | KMT2ABCL3PDGFRBKITKDR | |
| SCHEMBL6035353 | 0.86 | MAP2K1 (0.50) | KMT2ABCL3PDGFRBKITKDR | |
| SCHEMBL6036039 | 0.85 | CYP1A2 (0.51) | KMT2ABCL3PDGFRBKITKDR | |
| SCHEMBL6035676 | 0.84 | CYP1A2 (0.49) | KMT2ABCL3PDGFRBKITKDR | |
| SCHEMBL7785349 | 0.84 | LMNA (0.44) | KMT2ABCL3PDGFRBKITKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000037141-A9 | COMBINATION CHEMOTHERAPY | WARNER LAMBERT CO (US) | 2000-12-07 | — | — | WO | disclosed |