SCHEMBL8169264

SCHEMBL8169264

C=C(C)C(=O)OCCCCCCCCCCCCCCCCCCC.CCCCCCCCCCCCCCCCCCC=C(C)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.69
EP300 Q09472 1/20 0.46
POLB P06746 1/20 0.44
APEX1 P27695 1/20 0.44
HTT P42858 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HCAR2 Q8TDS4 2/20 0.42
FAAH O00519 2/20 0.42
THRB P10828 1/20 0.41
NAAA Q02083 1/20 0.40
RAD52 P43351 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
EPHX2 P34913 2/20 0.39
EPHX1 P07099 1/20 0.38
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8534212 1.00 TSHR (0.69) TSHREP300POLBAPEX1HTT
SCHEMBL1512984 1.00 TSHR (0.69) TSHREP300POLBAPEX1HTT
SCHEMBL27812913 1.00 TSHR (0.69) TSHREP300POLBAPEX1HTT
SCHEMBL28002688 1.00 TSHR (0.69) TSHREP300POLBAPEX1HTT
SCHEMBL11302570 1.00 TSHR (0.69) TSHREP300POLBAPEX1HTT
SCHEMBL15284904 1.00 TSHR (0.69) TSHREP300POLBAPEX1HTT
SCHEMBL35937 1.00 TSHR (0.69) TSHREP300POLBAPEX1HTT
SCHEMBL20745132 0.93 TSHR (0.54) TSHREP300POLBAPEX1HTT
SCHEMBL9517498 0.92 TSHR (0.58) TSHREP300POLBAPEX1HTT
Methacrylic Acid SCHEMBL11249803 0.90 TSHR (0.61) TSHREP300POLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1015532-A2 METHOD FOR IMPROVING LOW-TEMPERATURE FLUIDITY OF LUBRICATING OILS USING HIGH- AND LOW-MOLECULAR WEIGHT POLYMER ADDITIVE MIXTURES Röhm RohMax Holding GmbH (DE) 2000-07-05 EP disclosed
WO-1999010454-A2 MIXTURES OF HIGH- AND LOW-MOLECULAR WEIGHT POYMERIC ADDITIVES FOR THE IMPROVEMENT OF THE LOW-TEMPERATURE FLUIDITY OF LUBRICATING OILS Röhm RohMax Holding GmbH (DE) 1999-03-04 WO disclosed