SCHEMBL8534212

SCHEMBL8534212

C=C(C)C(=O)OCCCCCCCCCCCC.CCCCCCCCCCCCCCCCCCC=C(C)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.69
EP300 Q09472 1/20 0.46
POLB P06746 1/20 0.44
APEX1 P27695 1/20 0.44
HTT P42858 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HCAR2 Q8TDS4 2/20 0.42
FAAH O00519 2/20 0.42
THRB P10828 1/20 0.41
NAAA Q02083 1/20 0.40
RAD52 P43351 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
EPHX2 P34913 2/20 0.39
EPHX1 P07099 1/20 0.38
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1512984 1.00 TSHR (0.69) TSHREP300POLBAPEX1HTT
SCHEMBL27812913 1.00 TSHR (0.69) TSHREP300POLBAPEX1HTT
SCHEMBL28002688 1.00 TSHR (0.69) TSHREP300POLBAPEX1HTT
SCHEMBL11302570 1.00 TSHR (0.69) TSHREP300POLBAPEX1HTT
SCHEMBL8169264 1.00 TSHR (0.69) TSHREP300POLBAPEX1HTT
SCHEMBL15284904 1.00 TSHR (0.69) TSHREP300POLBAPEX1HTT
SCHEMBL35937 1.00 TSHR (0.69) TSHREP300POLBAPEX1HTT
SCHEMBL20745132 0.93 TSHR (0.54) TSHREP300POLBAPEX1HTT
SCHEMBL9517498 0.92 TSHR (0.58) TSHREP300POLBAPEX1HTT
Methacrylic Acid SCHEMBL11249803 0.90 TSHR (0.61) TSHREP300POLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2756053-B2 SURFACTANT RESPONSIVE DISPERSION POLYMERIZED MICRO-GELS LUBRIZOL ADVANCED MAT INC (US) 2019-04-03 EP claimed
US-20150342860-A1 IRRITATION MITIGATING POLYMERS AND USES THEREFOR LUBRIZOL ADVANCED MATERIALS, INC. (US) 2015-12-03 US claimed
EP-2756051-B1 SURFACTANT RESPONSIVE MICRO-GELS LUBRIZOL ADVANCED MAT INC (US) 2015-11-18 EP claimed
EP-2756053-B1 SURFACTANT RESPONSIVE DISPERSION POLYMERIZED MICRO-GELS LUBRIZOL ADVANCED MAT INC (US) 2015-11-18 EP claimed
EP-2934679-A2 IRRITATION MITIGATING POLYMERS AND USES THEREFOR Lubrizol Advanced Materials, Inc. (US) 2015-10-28 EP claimed
US-9096755-B2 Surfactant responsive micro-gels LUBRIZOL ADVANCED MATERIALS, INC. (US) 2015-08-04 US claimed
US-20140364511-A1 Surfactant Responsive Micro-Gels LUBRIZOL ADVANCED MATERIALS, INC. (US) 2014-12-11 US claimed
US-20140341957-A1 Surfactant Responsive Dispersion Polymerized Micro-Gels LUBRIZOL ADVANCED MATERIALS, INC. (US) 2014-11-20 US claimed
EP-2756051-A1 SURFACTANT RESPONSIVE MICRO-GELS Lubrizol Advanced Materials, Inc. (US) 2014-07-23 EP claimed
EP-2756053-A1 SURFACTANT RESPONSIVE DISPERSION POLYMERIZED MICRO-GELS Lubrizol Advanced Materials, Inc. (US) 2014-07-23 EP claimed
WO-2014099585-A2 IRRITATION MITIGATING POLYMERS AND USES THEREFOR LUBRIZOL ADVANCED MATERIALS, INC. (US) 2014-06-26 WO claimed
WO-2013040167-A1 SURFACTANT RESPONSIVE MICRO-GELS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-03-21 WO claimed
WO-2013040178-A1 SURFACTANT RESPONSIVE DISPERSION POLYMERIZED MICRO-GELS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-03-21 WO claimed
EP-0864626-A1 Anti-icing fluids THE B.F. GOODRICH COMPANY (US) 1998-09-16 EP claimed
US-20160168299-A1 HALOGENATED LATEX POLYMER AND METHOD OF MAKING SAME ROHM AND HAAS CHEMICALS LLC 2016-06-16 US disclosed
EP-2756051-B1 SURFACTANT RESPONSIVE MICRO-GELS LUBRIZOL ADVANCED MAT INC (US) 2015-11-18 EP disclosed
EP-2756053-B1 SURFACTANT RESPONSIVE DISPERSION POLYMERIZED MICRO-GELS LUBRIZOL ADVANCED MAT INC (US) 2015-11-18 EP disclosed
US-4628076-A PROTECTIVE AND DECORATIVE FILMS PPG INDUSTRIES, INC. (US) 1986-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140341957-A1 Surfactant Responsive Dispersion Polymerized Micro-Gels MSN, ACTB, ALG1 TSHR 2706/4885EP300 2254/4885POLB 933/4885
US-20150342860-A1 IRRITATION MITIGATING POLYMERS AND USES THEREFOR CUTA, NOTUM, CCL11 TSHR 3903/4885EP300 3311/4885POLB 2237/4885
US-20140364511-A1 Surfactant Responsive Micro-Gels MSN, STIP1, SMURF1 TSHR 1918/4885EP300 1340/4885POLB 1745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.