Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.81 |
| ▸ | F2 | P00734 | 4/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8163686 | 0.90 | F10 (1.00) | F10F2 | |
| SCHEMBL8164883 | 0.89 | F10 (0.78) | F10F2 | |
| SCHEMBL8156386 | 0.89 | F10 (0.81) | F10 | |
| SCHEMBL8165024 | 0.81 | F10 (0.80) | F10 | |
| SCHEMBL8406109 | 0.80 | F10 (0.76) | F10F2KLKB1 | |
| SCHEMBL8170059 | 0.80 | F10 (0.81) | F10F2 | |
| SCHEMBL8163632 | 0.79 | F10 (0.80) | F10 | |
| SCHEMBL8158194 | 0.78 | F10 (0.84) | F10F2 | |
| SCHEMBL8164228 | 0.78 | F10 (1.00) | F10 | |
| SCHEMBL8170227 | 0.78 | F10 (0.77) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |