Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.76 |
| ▸ | F2 | P00734 | 8/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404439 | 0.89 | F10 (0.68) | F10F2PRSS1KLKB1 | |
| SCHEMBL8158194 | 0.86 | F10 (0.84) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8170306 | 0.86 | F10 (1.00) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8169270 | 0.80 | F10 (0.81) | F10F2KLKB1 | |
| SCHEMBL8163632 | 0.79 | F10 (0.80) | F10 | |
| SCHEMBL8166112 | 0.78 | F10 (0.81) | F10 | |
| SCHEMBL8158231 | 0.77 | F10 (0.81) | F10 | |
| SCHEMBL8163627 | 0.76 | F10 (0.80) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8165499 | 0.76 | F10 (0.81) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6769780 | 0.75 | F10 (0.55) | F10KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |