Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.69 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | GLP1R | P43220 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177255 | 0.90 | CCR2 (0.75) | CCR2 | |
| SCHEMBL8218145 | 0.86 | CCR2 (0.91) | CCR2 | |
| SCHEMBL8218143 | 0.86 | CCR2 (0.91) | CCR2 | |
| SCHEMBL8176497 | 0.82 | CCR2 (0.81) | CCR2 | |
| SCHEMBL8169373 | 0.82 | CCR2 (0.73) | CCR2 | |
| SCHEMBL8169717 | 0.81 | CCR2 (0.79) | CCR2 | |
| SCHEMBL8181941 | 0.80 | CCR2 (0.67) | CCR2 | |
| SCHEMBL8209218 | 0.79 | CCR2 (1.00) | CCR2 | |
| SCHEMBL6204468 | 0.79 | CCR2 (1.00) | CCR2 | |
| SCHEMBL8177334 | 0.77 | CCR2 (0.83) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069815-A1 | UREIDO-SUBSTITUTED CYCLIC AMINE DERIVATIVES AND THEIR USE AS DRUG | TEIJIN LIMITED (JP) | 2000-11-23 | — | — | WO | disclosed |