Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169343 | 0.96 | MAPT (0.48) | ALDH1A1HPGDKDM4ENPSR1LMNA | |
| SCHEMBL8168235 | 0.92 | MAPT (0.52) | ALDH1A1HPGDKDM4ENPSR1LMNA | |
| SCHEMBL8168502 | 0.91 | HCAR2 (0.54) | ALDH1A1HPGDKDM4ENPSR1LMNA | |
| SCHEMBL8168508 | 0.87 | HCAR2 (0.55) | ALDH1A1HPGDKDM4ENPSR1LMNA | |
| SCHEMBL8163026 | 0.82 | HCAR2 (0.59) | ALDH1A1HPGDKDM4ENPSR1LMNA | |
| SCHEMBL8173573 | 0.77 | MAPT (0.46) | ALDH1A1KDM4ELMNAGAAABCG2 | |
| SCHEMBL8172315 | 0.76 | KDM4E (0.52) | ALDH1A1HPGDKDM4ENPSR1LMNA | |
| SCHEMBL4666922 | 0.76 | ABCG2 (0.55) | ALDH1A1HPGDKDM4ENPSR1LMNA | |
| SCHEMBL4666926 | 0.76 | ABCG2 (0.55) | ALDH1A1HPGDKDM4ENPSR1LMNA | |
| SCHEMBL8161855 | 0.75 | LTB4R (0.54) | ALDH1A1HPGDKDM4ENPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022307-A | ANGIOGENESIS INHIBITOR | AMERICAN CYANAMID COMPANY (US) | 2000-02-08 | — | — | US | disclosed |