Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.47 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169394 | 0.97 | MTNR1A (0.44) | MTNR1AMTNR1BSPR | |
| SCHEMBL7824776 | 0.85 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL7836978 | 0.83 | MTNR1A (0.52) | MTNR1AMTNR1B | |
| SCHEMBL8169504 | 0.78 | HTR2A (0.59) | MTNR1AMTNR1BSPRKDM4E | |
| SCHEMBL7808180 | 0.76 | HTR2C (0.55) | KDM4E | |
| SCHEMBL8169370 | 0.74 | HTR2A (0.60) | MTNR1AMTNR1BSPR | |
| SCHEMBL8162966 | 0.72 | MTNR1A (0.74) | MTNR1AMTNR1BKDM4E | |
| SCHEMBL8162108 | 0.71 | MTNR1A (0.54) | MTNR1AMTNR1BKDM4E | |
| SCHEMBL8169871 | 0.69 | MTNR1A (0.75) | MTNR1AMTNR1B | |
| SCHEMBL8161912 | 0.68 | MTNR1A (0.50) | MTNR1AMTNR1BSPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071946-A | FOR TREATING DISORDERS OF THE MELATONINERGIC SYSTEM, SLEEP DISORDERS, CIRCADIAN RHYTHM DISORDERS | ADIR ET COMPAGNIE (FR) | 2000-06-06 | — | — | US | disclosed |