Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169561 | 1.00 | ALDH1A1 (0.44) | ALDH1A1CYP24A1CNR2POLBCYP1A2 | |
| SCHEMBL8169563 | 1.00 | ALDH1A1 (0.44) | ALDH1A1CYP24A1CNR2POLBCYP1A2 | |
| SCHEMBL27898429 | 0.82 | MEN1 (0.37) | ALDH1A1CYP24A1 | |
| SCHEMBL6900713 | 0.82 | DHODH (0.32) | ALDH1A1CNR2POLBCYP2C19LMNA | |
| SCHEMBL6900706 | 0.82 | DHODH (0.32) | ALDH1A1CNR2POLBCYP2C19LMNA | |
| SCHEMBL8165805 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CNR2POLBCYP1A2CYP2C9 | |
| SCHEMBL8165807 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CNR2POLBCYP1A2CYP2C9 | |
| SCHEMBL8165802 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CNR2POLBCYP1A2CYP2C9 | |
| SCHEMBL16039622 | 0.77 | ALDH1A1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL16039619 | 0.77 | ALDH1A1 (0.41) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6133457-A | CRYPTOPHYCIN COMPOUNDS HAVING ANTIMICROTUBULE ACTIVITY; ANTIMETABOLITES | ELI LILLY AND COMPANY (US) | 2000-10-17 | — | — | US | disclosed |