Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | GRN | P28799 | 1/20 | 0.48 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380085 | 0.84 | SLC6A4 (0.48) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL2444598 | 0.83 | HPGD (0.46) | CYP3A4L3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL4328573 | 0.82 | SLC6A4 (0.55) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL10383881 | 0.81 | SLC6A4 (0.53) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL6469200 | 0.81 | GRN (0.54) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL8082304 | 0.81 | SLC6A4 (0.59) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL7470435 | 0.81 | SLC6A4 (0.53) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL17512989 | 0.78 | CYP3A4 (0.55) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| SCHEMBL9372527 | 0.78 | PPARA (0.48) | SLC6A4SLC6A2HTR2AHRH1HTR2B | |
| 1,4-Dichlorobenzene SCHEMBL28285971 | 0.78 | MEN1 (0.44) | SLC6A4SLC6A2HTR2AHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000044703-A2 | A NOVEL SYNTHETIC ROUTE FOR OBTAINING 1-(4-CHLOROPHENYL)-4,4-DIMETHYL-PENTANE-3-ONE | MAKHTESHIM CHEMICAL WORKS LTD. (IL) | 2000-08-03 | — | — | WO | claimed |
| EP-0355350-B1 | PROCESS FOR THE PREPARATION OF 4,4-DIMETHYL-1-(P-CHLOROPHENYL)-PENTAN-3-ONE | BAYER AG (DE) | 1992-11-25 | — | — | EP | claimed |
| CN-109456288-A | A kind of preparation method of tebuconazole intermediate | 江苏七洲绿色化工股份有限公司 | 2019-03-12 | — | — | CN | disclosed |
| WO-2000044703-A2 | A NOVEL SYNTHETIC ROUTE FOR OBTAINING 1-(4-CHLOROPHENYL)-4,4-DIMETHYL-PENTANE-3-ONE | MAKHTESHIM CHEMICAL WORKS LTD. (IL) | 2000-08-03 | — | — | WO | disclosed |
| EP-0355350-B1 | PROCESS FOR THE PREPARATION OF 4,4-DIMETHYL-1-(P-CHLOROPHENYL)-PENTAN-3-ONE | BAYER AG (DE) | 1992-11-25 | — | — | EP | disclosed |
| US-4994480-A | Protecting plants, industrial materials | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-19 | — | — | US | disclosed |
| EP-0355350-A1 | Process for the preparation of 4,4-dimethyl-1-(p-chlorophenyl)-pentan-3-one | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |