Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 1/20 | 0.53 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.53 |
| ▸ | BTN3A1 | O00481 | 3/20 | 0.50 |
| ▸ | MVD | P53602 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10880122 | 0.96 | ITPR3 (0.50) | ITPR3ITPR1BTN3A1MVDLMNA | |
| SCHEMBL18798606 | 0.96 | ITPR3 (0.50) | ITPR3ITPR1BTN3A1MVDLMNA | |
| SCHEMBL18798611 | 0.96 | ITPR3 (0.50) | ITPR3ITPR1BTN3A1MVDLMNA | |
| SCHEMBL10878442 | 0.94 | BTN3A1 (0.48) | ITPR3ITPR1BTN3A1MVDLMNA | |
| SCHEMBL8829466 | 0.92 | BTN3A1 (0.47) | ITPR3ITPR1BTN3A1MVDGGPS1 | |
| SCHEMBL10880174 | 0.90 | BTN3A1 (0.46) | ITPR3ITPR1BTN3A1MVDLMNA | |
| SCHEMBL23845594 | 0.88 | BTN3A1 (0.44) | ITPR3ITPR1BTN3A1MVDGGPS1 | |
| SCHEMBL260134 | 0.88 | BTN3A1 (0.44) | ITPR3ITPR1BTN3A1MVDGGPS1 | |
| SCHEMBL3405906 | 0.88 | BTN3A1 (0.44) | ITPR3ITPR1BTN3A1MVDGGPS1 | |
| Putrescine SCHEMBL27732786 | 0.88 | BTN3A1 (0.44) | ITPR3ITPR1BTN3A1MVDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000074692-A1 | A METHOD USING POTASSIUM DIHYDROGEN PHOSPHATE TO REDUCE CALCIFICATION OF TISSUE | FREMANTLE HEART INSTITUTE PTY LTD (AU) | 2000-12-14 | — | — | WO | disclosed |
| US-4615977-A | AMINE DERIVATIVES PROMOTE GROWTH WITH LOW SERUM CONCENTRATIONS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-10-07 | — | — | US | disclosed |
| EP-0082974-B1 | METHOD FOR THE CULTIVATION OF NORMAL DIPLOID CELLS AND CULTIVATION MEDIUM USED THEREFOR | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0082974-A2 | Method for the cultivation of normal diploid cells and cultivation medium used therefor | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-07-06 | — | — | EP | disclosed |