Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817589 | 0.77 | KMT2A (0.37) | MAPTKMT2A | |
| SCHEMBL818792 | 0.76 | GBA1 (0.39) | ATMLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL817944 | 0.75 | KMT2A (0.44) | ATMLMNAMAPTSMN1; SMN2TSHR | |
| SCHEMBL27391060 | 0.69 | CES2 (0.34) | CES2CES1ESR1KDM1ATSHR | |
| SCHEMBL2767081 | 0.69 | ATM (0.48) | ATMCES2CES1ESR1LMNA | |
| SCHEMBL2767155 | 0.69 | ATM (0.48) | ATMCES2CES1ESR1LMNA | |
| SCHEMBL2767079 | 0.69 | ATM (0.48) | ATMCES2CES1ESR1LMNA | |
| SCHEMBL28148537 | 0.67 | ESR1 (0.53) | ATMCES2CES1ESR1LMNA | |
| SCHEMBL1035354 | 0.67 | ESR1 (0.56) | CES2CES1ESR1LMNABLM | |
| SCHEMBL11844374 | 0.67 | ESR1 (0.56) | CES2CES1ESR1LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275756-A1 | CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-10 | — | — | US | disclosed |