Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856019 | 0.78 | DPP4 (0.61) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL872342 | 0.78 | DPP4 (0.61) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL20543239 | 0.78 | DPP4 (0.61) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL5853830 | 0.78 | SLC6A4 (0.63) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL294761 | 0.78 | DPP4 (0.96) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| Hydrochloric Acid SCHEMBL3520274 | 0.77 | DPP4 (0.92) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL21351801 | 0.77 | SLC6A4 (0.61) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL49169 | 0.77 | DPP4 (0.59) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL6409381 | 0.76 | DPP4 (0.63) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL8122483 | 0.76 | DPP4 (0.63) | DPP4SLC6A4SLC6A2SLC6A3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019367-A1 | DERIVATIVES OF 2,5- AND 3,5-DISUBSTITUTED ANILINES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-07-19 | — | — | EP | claimed |
| WO-1999007672-A1 | DERIVATIVES OF 2,5- AND 3,5-DISUBSTITUTED ANILINES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-02-18 | — | — | WO | claimed |
| EP-1019367-A1 | DERIVATIVES OF 2,5- AND 3,5-DISUBSTITUTED ANILINES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999007672-A1 | DERIVATIVES OF 2,5- AND 3,5-DISUBSTITUTED ANILINES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-02-18 | — | — | WO | disclosed |