Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497930 | 0.98 | DPP4 (0.63) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL7447078 | 0.93 | DPP4 (0.57) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL497605 | 0.89 | MAOA (0.60) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL497847 | 0.81 | DPP4 (0.59) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL5853830 | 0.78 | SLC6A4 (0.63) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL8170334 | 0.78 | DPP4 (0.61) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL20543239 | 0.78 | DPP4 (0.61) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL294761 | 0.78 | DPP4 (0.96) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL2856019 | 0.78 | DPP4 (0.61) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL251313 | 0.78 | DPP4 (0.55) | DPP4SLC6A4SLC6A2SLC6A3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619190-A1 | SUBSTITUTED OXADIAZOLE COMPOUNDS AND THEIR USE AS S1P1 AGONISTS | Bristol-Myers Squibb Company (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012040532-A1 | SUBSTITUTED OXADIAZOLE COMPOUNDS AND THEIR USE AS S1P1 AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-29 | — | — | WO | disclosed |
| CN-1162427-C | Amine derivatives compounds | ������������ʽ���� | 2004-08-18 | — | — | CN | disclosed |
| CN-1354750-A | Amine derivatives compounds | SANKYO CO (JP) | 2002-06-19 | — | — | CN | disclosed |