Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 20/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8175287 | 0.87 | KIF11 (0.63) | KIF11 | |
| SCHEMBL3475080 | 0.79 | KIF11 (0.67) | KIF11KCNH2 | |
| SCHEMBL4397129 | 0.78 | KIF11 (0.78) | KIF11 | |
| SCHEMBL27608746 | 0.78 | KIF11 (0.78) | KIF11 | |
| SCHEMBL17189279 | 0.78 | KIF11 (0.53) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17502350 | 0.77 | KIF11 (0.53) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8346825 | 0.76 | KIF11 (0.60) | KIF11 | |
| SCHEMBL2679441 | 0.76 | KIF11 (1.00) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6551716 | 0.76 | KIF11 (0.61) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4399790 | 0.75 | KIF11 (1.00) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127341-A | AMINOMETHYL-N-(1-((2-(2-THIENYL)-1-(1-CARBAMOYL-5 -AMINOPENTYLCARBAMOYL)ETHYL)-N-METHYLCARBAMOYL)-2-(2 -NAPTHYL)ETHYL)BENZAMIDE, FOR EXAMPLE; ADMINISTERING TO STIMULATE GROWTH, MILK OR WOOL PRODUCTION IN ANIMALS | NOVO NORDISK A/S (DK) | 2000-10-03 | — | — | US | disclosed |
| EP-1005484-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 2000-06-07 | — | — | EP | disclosed |
| WO-1998058950-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-12-30 | — | — | WO | disclosed |