Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502180 | 0.88 | PTGER1 (0.51) | HPGDSMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL7470900 | 0.82 | ALDH1A1 (0.51) | HPGDLMNAHDAC6SMN1; SMN2RAB9A | |
| SCHEMBL30141076 | 0.80 | CYP19A1 (0.54) | HPGDLMNASMPD1HDAC1HDAC8 | |
| SCHEMBL3245222 | 0.80 | SMPD1 (0.67) | HPGDLMNASMPD1HDAC1HDAC8 | |
| SCHEMBL2854822 | 0.79 | HPGD (0.56) | HPGDLMNASMPD1HDAC1HDAC8 | |
| SCHEMBL7612296 | 0.79 | ALDH1A1 (0.43) | HPGDLMNASMN1; SMN2RAB9AMAPT | |
| SCHEMBL8169201 | 0.79 | PDE4B (0.47) | ALDH1A1 | |
| SCHEMBL3721195 | 0.79 | HPGD (0.58) | HPGDLMNASMPD1HDAC1HDAC8 | |
| SCHEMBL559537 | 0.79 | NOTUM (0.58) | HPGDLMNASMPD1HDAC1HDAC8 | |
| SCHEMBL8164103 | 0.78 | PDE4A (0.43) | HPGDLMNASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6137003-A | Bis (haloethyl) aminobenzene derivatives | SHIONOGI BIORESEARCH (US) | 2000-10-24 | — | — | US | disclosed |