SCHEMBL8170703

SCHEMBL8170703

N#Cc1ccc(N2C[C@H](CNC(=O)C3CC=C(Cl)S3)OC2=O)cc1Cl

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 19/20 0.52
MAOB P27338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7999551 0.87 GRM2 (0.48) F10
SCHEMBL13479570 0.82 F10 (0.66) F10MAOB
SCHEMBL13262748 0.80 F10 (0.78) F10
SCHEMBL8246602 0.78 F10 (0.66) F10
SCHEMBL13479673 0.78 F10 (0.66) F10MAOB
SCHEMBL7982750 0.78 F10 (0.66) F10
SCHEMBL8203282 0.77 F10 (0.70) F10MAOB
SCHEMBL8210966 0.76 F10 (0.51) F10MAOB
SCHEMBL7994083 0.76 F10 (0.45) F10
SCHEMBL7983038 0.76 F10 (0.48) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008140220-A1 FXA INHIBITORS WITH CYCLIC AMIDINES AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF LEGOCHEM BIOSCIENCE LTD. (KR) 2008-11-20 WO disclosed