⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28290428 | 0.97 | ALDH1A1 (0.35) | — | |
| SCHEMBL15051588 | 0.97 | — | — | |
| SCHEMBL259495 | 0.90 | — | — | |
| SCHEMBL25269862 | 0.87 | ALDH1A1 (0.44) | — | |
| SCHEMBL922730 | 0.87 | — | — | |
| SCHEMBL3912551 | 0.87 | ALDH1A1 (0.44) | — | |
| SCHEMBL25259503 | 0.87 | ALDH1A1 (0.44) | — | |
| SCHEMBL9119002 | 0.87 | ALDH1A1 (0.44) | — | |
| SCHEMBL100726 | 0.87 | — | — | |
| SCHEMBL27056299 | 0.87 | ALDH1A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2623 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4610251-A1 | HEPTAFLUOROISOPROPYL-CONTAINING BISAMIDE COMPOUND AND INTERMEDIATE COMPOUND THEREOF, AND PREPARATION METHODS THEREFOR AND USE THEREOF | Zhejiang Udragon Pesticides And Chemicals Co., Ltd. (CN) | 2025-09-03 | — | — | EP | claimed |
| CN-119119135-A | Rigid bridged metallocene-fluorene metal compound and preparation method thereof | 浙江昇茂催化技术有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-118684679-A | Phthalocyanine compound, acidic substance alarm system and application | 兰州大学 | 2024-09-24 | — | — | CN | claimed |
| WO-2024094024-A1 | POLYMER, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国石油天然气股份有限公司 | 2024-05-10 | — | — | WO | claimed |
| WO-2024087613-A1 | HEPTAFLUOROISOPROPYL-CONTAINING BISAMIDE COMPOUND AND INTERMEDIATE COMPOUND THEREOF, AND PREPARATION METHODS THEREFOR AND USE THEREOF | 浙江宇龙药业有限公司 | 2024-05-02 | — | — | WO | claimed |
| CN-115974717-A | Heptafluoroisopropyl-containing bisamide compound and intermediate compound thereof, and preparation method and application thereof | 浙江宇龙药业有限公司 | 2023-04-18 | — | — | CN | claimed |
| US-20220416316-A1 | Flame Retardants For Battery Electrolytes | ALBEMARLE CORPORATION | 2022-12-29 | — | — | US | claimed |
| CN-114149450-B | Industrial preparation method of key intermediate of intraocular pressure resistant drug | 上海彩迩文生化科技有限公司 | 2022-12-09 | — | — | CN | claimed |
| EP-4062479-A1 | FLAME RETARDANTS FOR BATTERY ELECTROLYTES | ALBEMARLE CORPORATION (US) | 2022-09-28 | — | — | EP | claimed |
| CN-111171197-B | Method for preparing high-activity polyisobutylene by using bifunctional initiator and application | 北京石油化工学院 | 2022-08-02 | — | — | CN | claimed |
| CN-102056914-A | Process for the preparation of 3,4-dihydro-2H-thien[3,2-E]-1,2-thiazin-4-ol 1, 1-dioxide derivatives and intermediates | PHF SA | 2011-05-11 | — | — | CN | claimed |
| EP-2303856-A2 | PROCESS FOR THE PREPARATION OF 3,4-DIHYDRO-2H-THIEN[3,2-E]-1,2-THIAZIN-4-OL 1, 1-DIOXIDE DERIVATIVES AND INTERMEDIATES | PHF SA (CH) | 2011-04-06 | — | — | EP | claimed |
| WO-2010103550-A2 | PROCESS FOR THE PREPARATION OF INTERMEDIATES | INDOCO REMEDIES LIMITED (IN) | 2010-09-16 | — | — | WO | claimed |
| WO-2010004457-A2 | PROCESS FOR THE PREPARATION OF BRINZOLAMIDE | PHF SA (CH) | 2010-01-14 | — | — | WO | claimed |
| US-20100009977-A1 | Process for the preparation of (R)-(+)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide-1,1-dioxide. | USV LTD. (IN) | 2010-01-14 | — | — | US | claimed |
| EP-2079749-A2 | IMPROVED PROCESS FOR THE PREPARATION OF (R)-(+)-4-(ETHYIAMINO)-3,4-DIHYDRO-2-(3- METHOXYPROPYL)-2H-THIENO[3,2-E]-L,2-THIAZINE-6-SULFONAMIDE-L,L-DIOXIDE | USV LIMITED (IN) | 2009-07-22 | — | — | EP | claimed |
| WO-2008062463-A2 | IMPROVED PROCESS FOR THE PREPARATION OF (R)-(+)-4-(ETHYIAMINO)-3,4-DIHYDRO-2-(3- METHOXYPROPYL)-2H-THIENO[3,2-E]-L,2-THIAZINE-6-SULFONAMIDE-L,L-DIOXIDE | USV LIMITED (IN) | 2008-05-29 | — | — | WO | claimed |
| EP-0617038-B1 | Preparation of carbonic anhydrase inhibitors | ALCON LAB INC (US) | 2001-09-05 | — | — | EP | claimed |
| WO-1996010573-A1 | ENANTIOSELECTIVE SYNTHESIS OF SULFONAMIDE INTERMEDIATES | ALCON LABORATORIES, INC. (US) | 1996-04-11 | — | — | WO | claimed |
| EP-0617038-A1 | Preparation of carbonic anhydrase inhibitors | ALCON LABORATORIES, INC. (US) | 1994-09-28 | — | — | EP | claimed |