Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | NAT1 | P18440 | 3/20 | 0.50 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181146 | 0.79 | PIM1 (0.71) | NAT1CA2EPHX1RAB9AKMT2A | |
| SCHEMBL8171935 | 0.78 | NAT1 (0.63) | NAT1CISD1CA2EPHX1RAB9A | |
| SCHEMBL8171937 | 0.78 | NAT1 (0.63) | NAT1CISD1CA2EPHX1RAB9A | |
| SCHEMBL8190448 | 0.77 | IDH1 (0.53) | NAT1MMP3MMP13GSK3B | |
| SCHEMBL8190447 | 0.77 | IDH1 (0.53) | NAT1MMP3MMP13GSK3B | |
| SCHEMBL12892048 | 0.73 | CRHBP (0.72) | RAB9AKMT2AKDM4ENPC1HSP90AA1 | |
| SCHEMBL15347679 | 0.73 | CRHBP (0.72) | RAB9AKMT2AKDM4ENPC1HSP90AA1 | |
| SCHEMBL15347480 | 0.73 | CRHBP (0.72) | RAB9AKMT2AKDM4ENPC1HSP90AA1 | |
| SCHEMBL8179901 | 0.73 | PTP4A3 (0.74) | NAT1CISD1PTP4A3PIM1GSK3B | |
| SCHEMBL8179904 | 0.73 | PTP4A3 (0.74) | NAT1CISD1PTP4A3PIM1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018748-A1 | RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |