SCHEMBL8172159

SCHEMBL8172159

CC(C)c1cccc(C(C)C)c1N=CCc1cccc(-c2ccccn2)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.41
HTT P42858 3/20 0.41
LMNA P02545 3/20 0.41
CCR1 P32246 3/20 0.41
CCR5 P51681 3/20 0.41
CCR8 P51685 3/20 0.41
TP53 P04637 2/20 0.41
ALOX15 P16050 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ALPL P05186 1/20 0.41
HSP90AA1 P07900 1/20 0.41
ALPI P09923 1/20 0.41
ALPG P10696 1/20 0.41
MAPK1 P28482 1/20 0.41
PDE10A Q9Y233 1/20 0.36
HCRTR1 O43613 1/20 0.36
HCRTR2 O43614 1/20 0.36
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8168226 0.99 KDM4E (0.41) KDM4EHTTLMNACCR1CCR5
Bromide SCHEMBL3698944 0.90 KDM4E (0.37) KDM4EHTTLMNACCR1CCR5
Bromide SCHEMBL3693101 0.90 KDM4E (0.37) KDM4EHTTLMNACCR1CCR5
Hydrochloric Acid SCHEMBL3691493 0.90 KDM4E (0.37) KDM4EHTTLMNACCR1CCR5
Hydrochloric Acid SCHEMBL3692218 0.90 KDM4E (0.37) KDM4EHTTLMNACCR1CCR5
SCHEMBL5589655 0.87 PIP4K2C (0.38) LMNACYP1A2PIP4K2CALDH1A1
SCHEMBL5693577 0.85 PIP4K2C (0.37) LMNACYP1A2PIP4K2CALDH1A1
SCHEMBL3690177 0.84 KDM4E (0.46) KDM4EHTTLMNACCR1CCR5
Hydrochloric Acid SCHEMBL7764129 0.84 GABRA1 (0.33) LMNAALOX15CYP1A2BLMHIF1A
Hydrochloric Acid SCHEMBL7149371 0.84 GABRA1 (0.33) LMNAALOX15CYP1A2BLMHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000058320-A1 PYRIDINE.IMINE POLYMERISATION CATALYSTS BP CHEMICALS LIMITED (GB) 2000-10-05 WO disclosed