Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819529 | 0.92 | TSHR (0.42) | ALDH1A1LMNATSHRESR1TP53 | |
| SCHEMBL817820 | 0.92 | TSHR (0.40) | ALDH1A1LMNATSHRESR1TDP1 | |
| SCHEMBL818562 | 0.91 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRESR1TP53 | |
| SCHEMBL818575 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TSHRCHRM1ADORA2BMAPT | |
| SCHEMBL818337 | 0.79 | ALDH1A1 (0.38) | ALDH1A1LMNATSHRESR1TDP1 | |
| SCHEMBL818264 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRESR1TDP1 | |
| SCHEMBL819753 | 0.77 | ALDH1A1 (0.48) | ALDH1A1LMNATSHRTDP1CYP3A4 | |
| SCHEMBL818696 | 0.75 | ALDH1A1 (0.37) | ALDH1A1LMNATSHRESR1TDP1 | |
| SCHEMBL818003 | 0.71 | KDM4E (0.34) | ALDH1A1LMNATDP1KDM4EMAPT | |
| SCHEMBL817673 | 0.71 | TSHR (0.43) | ALDH1A1LMNATSHRESR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |