Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8509434 | 1.00 | EPHX1 (0.39) | EPHX1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL6837215 | 1.00 | EPHX1 (0.39) | EPHX1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9679048 | 1.00 | EPHX1 (0.39) | EPHX1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8508684 | 1.00 | EPHX1 (0.39) | EPHX1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8168467 | 1.00 | EPHX1 (0.39) | EPHX1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL6837104 | 1.00 | EPHX1 (0.39) | EPHX1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8169250 | 0.85 | MAPT (0.41) | EPHX1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8161726 | 0.85 | MAPT (0.41) | EPHX1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8408205 | 0.77 | KMT2A (0.40) | MEN1KMT2AHDAC4HDAC3HDAC7 | |
| SCHEMBL9680139 | 0.72 | EPHX1 (0.41) | EPHX1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030207935-A1 | Novel optically active clausenamides, process of the preparation thereof, pharmaceutical composition containing the same and their medical use | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES | 2003-11-06 | — | — | US | disclosed |
| US-20030207935-A1 | Novel optically active clausenamides, process of the preparation thereof, pharmaceutical composition containing the same and their medical use | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207935-A1 | Novel optically active clausenamides, process of the preparation thereof, pharmaceutical composition containing the same and their medical use | HIF1AN, HIF1A, CLN6 | EPHX1 455/4885MAPT 59/4885MEN1 2195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.