Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8508684 | 0.72 | EPHX1 (0.39) | EPHX1MAPTHTTALOX15HBB | |
| SCHEMBL6837215 | 0.72 | EPHX1 (0.39) | EPHX1MAPTHTTALOX15HBB | |
| SCHEMBL6837104 | 0.72 | EPHX1 (0.39) | EPHX1MAPTHTTALOX15HBB | |
| SCHEMBL8509434 | 0.72 | EPHX1 (0.39) | EPHX1MAPTHTTALOX15HBB | |
| SCHEMBL9679048 | 0.72 | EPHX1 (0.39) | EPHX1MAPTHTTALOX15HBB | |
| SCHEMBL8744100 | 0.72 | HSD17B2 (0.52) | — | |
| SCHEMBL8173575 | 0.72 | EPHX1 (0.39) | EPHX1MAPTHTTALOX15HBB | |
| SCHEMBL8169250 | 0.72 | MAPT (0.41) | EPHX1MAPTHTTALOX15HBB | |
| SCHEMBL8161726 | 0.72 | MAPT (0.41) | EPHX1MAPTHTTALOX15HBB | |
| SCHEMBL12926100 | 0.69 | HTT (0.41) | EPHX1MAPTHTTALOX15HBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093350-A | DEHYDROCYCLOCLAUSENAMIDE, ITS PREPARATION AND USE IN TREATING CEREBRAL HYPOXIA | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |