Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.65 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.65 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.65 |
| ▸ | PIM1 | P11309 | 9/20 | 0.64 |
| ▸ | NAT1 | P18440 | 4/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.60 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.55 |
| ▸ | CLK1 | P49759 | 1/20 | 0.55 |
| ▸ | CLK3 | P49761 | 1/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.55 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173600 | 1.00 | MTOR (0.65) | MTORRPTORMLST8PIM1NAT1 | |
| SCHEMBL1247436 | 0.84 | MTOR (0.64) | MTORPIM1NAT1CISD1MAOA | |
| SCHEMBL1247438 | 0.84 | MTOR (0.64) | MTORPIM1NAT1CISD1MAOA | |
| SCHEMBL21067541 | 0.82 | MAPK1 (0.56) | MTORRPTORMLST8PIM1GSK3B | |
| SCHEMBL23036920 | 0.80 | MTOR (1.00) | MTORRPTORMLST8PIM1NAT1 | |
| SCHEMBL622481 | 0.76 | PIK3CG (0.80) | MTORRPTORMLST8PIM1NAT1 | |
| SCHEMBL622482 | 0.76 | PIK3CG (0.80) | MTORRPTORMLST8PIM1NAT1 | |
| SCHEMBL622480 | 0.76 | PIK3CG (0.80) | MTORRPTORMLST8PIM1NAT1 | |
| SCHEMBL11315685 | 0.76 | NAT1 (0.70) | PIM1NAT1CA2EPHX1CISD1 | |
| SCHEMBL4416451 | 0.76 | NAT1 (1.00) | PIM1NAT1CA2EPHX1CISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018748-A1 | RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |