Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183726 | 0.92 | KMT2A (0.44) | KMT2AMAPK1MEN1USP2SMN1; SMN2 | |
| SCHEMBL8175290 | 0.90 | KMT2A (0.48) | KMT2AMAPK1MEN1USP2SMN1; SMN2 | |
| SCHEMBL7792101 | 0.90 | ALDH1A1 (0.43) | KMT2AMAPK1MEN1USP2SMN1; SMN2 | |
| SCHEMBL8444379 | 0.88 | MAPT (0.46) | KMT2AMAPK1MEN1USP2SMN1; SMN2 | |
| SCHEMBL8183709 | 0.88 | BRD9 (0.44) | KMT2AMAPK1MEN1USP2SMN1; SMN2 | |
| SCHEMBL8186107 | 0.87 | CHRNA7 (0.49) | KMT2AMAPK1MEN1USP2SMN1; SMN2 | |
| SCHEMBL8184601 | 0.87 | KMT2A (0.49) | KMT2AMAPK1MEN1USP2SMN1; SMN2 | |
| SCHEMBL8183724 | 0.87 | MAPT (0.47) | KMT2AMEN1MAPTBRD9ALDH1A1 | |
| SCHEMBL8184226 | 0.87 | KMT2A (0.46) | KMT2AMAPK1MEN1USP2SMN1; SMN2 | |
| SCHEMBL8440951 | 0.86 | BRD9 (0.43) | KMT2AMAPK1MEN1USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110934-A | Substituted benzamide derivatives and their use as anticonvulsants | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-08-29 | — | — | US | disclosed |
| EP-0906283-A1 | SUBSTITUTED BENZAMIDE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997048683-A1 | SUBSTITUTED BENZAMIDE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 1997-12-24 | — | — | WO | disclosed |