Toluene

Toluene

SCHEMBL8175017

C=C(C)C(=O)OCC1CO1.Cc1ccccc1

nearest known ligand 0.71

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.71
MGLL Q99685 6/20 0.47
GLA P06280 1/20 0.42
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL27077638 0.91 ALDH1A1 (0.76) ALDH1A1MGLLGLA
SCHEMBL7039423 0.90 ALDH1A1 (0.69) ALDH1A1MGLL
Biphenyl SCHEMBL28529224 0.90 ALDH1A1 (0.73) ALDH1A1MGLLTDP1
Benzene SCHEMBL7777595 0.89 ALDH1A1 (0.89) ALDH1A1MGLL
Benzene SCHEMBL28134170 0.89 ALDH1A1 (0.89) ALDH1A1MGLL
Phenol SCHEMBL727251 0.89 ALDH1A1 (0.71) ALDH1A1MGLLTDP1
Benzoic Acid SCHEMBL31405528 0.87 ALDH1A1 (0.69) ALDH1A1MGLLTDP1
Benzophenone SCHEMBL11799146 0.87 ALDH1A1 (0.69) ALDH1A1MGLL
Phenol SCHEMBL29076704 0.87 ALDH1A1 (0.69) ALDH1A1MGLLTDP1
Phthalic Acid SCHEMBL31350915 0.87 ALDH1A1 (0.69) ALDH1A1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110302562-B Preparation method of molecular imprinting open tubular column 武汉轻工大学 2021-08-27 CN disclosed
CN-110302562-A A kind of preparation method of molecular engram open tubular column 武汉轻工大学 2019-10-08 CN disclosed
US-6132860-A COUPLING POLYMER ADHESIVE TO ABRASIVE PARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-10-17 US disclosed