Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181723 | 0.92 | RARB (0.35) | RARBRAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8181726 | 0.92 | RARB (0.35) | RARBRAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8167129 | 0.91 | RARB (0.32) | RARBRAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8168553 | 0.90 | NPC1 (0.37) | RARBRAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7565302 | 0.88 | RARB (0.46) | RARBRAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7560051 | 0.88 | RARB (0.46) | RARBRAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7560836 | 0.88 | RARB (0.46) | RARBRAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7561626 | 0.88 | RARB (0.46) | RARBRAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7755270 | 0.88 | RARB (0.46) | RARBRAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7756078 | 0.88 | RARB (0.46) | RARBRAB9AMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6139924-A | CONTAINING A PYRIMIDINE RING | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-10-31 | — | — | US | disclosed |