SCHEMBL8181723 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	RARB	P10826	1/20	0.35

▸	RAB9A	P51151	4/20	0.32

▸	KDM4E	B2RXH2	2/20	0.32

▸	SMN1; SMN2	Q16637	2/20	0.32

▸	HSD17B10	Q99714	2/20	0.32

▸	MAPT	P10636	2/20	0.32

▸	MEN1	O00255	1/20	0.32

▸	USP2	O75604	1/20	0.32

▸	ALDH1A1	P00352	1/20	0.32

▸	GAA	P10253	1/20	0.32

▸	HPGD	P15428	1/20	0.32

▸	KMT2A	Q03164	1/20	0.32

▸	NPC1	O15118	2/20	0.31

▸	L3MBTL1	Q9Y468	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8181726	1.00	RARB (0.35)	RARBRAB9AKDM4ESMN1; SMN2HSD17B10
SCHEMBL8175083	0.92	RARB (0.35)	RARBRAB9AKDM4ESMN1; SMN2HSD17B10
SCHEMBL7560943	0.89	RARB (0.46)	RARBRAB9AKDM4ESMN1; SMN2HSD17B10
SCHEMBL6975888	0.89	RARB (0.46)	RARBRAB9AKDM4ESMN1; SMN2HSD17B10
SCHEMBL7558804	0.88	RARB (0.45)	RARBRAB9AKDM4ESMN1; SMN2HSD17B10
SCHEMBL7560022	0.88	RARB (0.45)	RARBRAB9AKDM4ESMN1; SMN2HSD17B10
SCHEMBL7106010	0.86	RARB (0.37)	RARBRAB9AKDM4ESMN1; SMN2HSD17B10
SCHEMBL7106009	0.86	RARB (0.37)	RARBRAB9AKDM4ESMN1; SMN2HSD17B10
SCHEMBL6975525	0.85	RARB (0.38)	RARBRAB9AKDM4ESMN1; SMN2HSD17B10
SCHEMBL6975523	0.85	RARB (0.38)	RARBRAB9AKDM4ESMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6139924-A	CONTAINING A PYRIMIDINE RING	3M INNOVATIVE PROPERTIES COMPANY (US)	2000-10-31	—	—	US	disclosed