Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | YWHAH | Q04917 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13931084 | 0.90 | EGFR (0.43) | THRATHRBMEN1KMT2AGFER | |
| SCHEMBL8171635 | 0.87 | MEN1 (0.53) | THRATHRBFOLH1PTGDR2MEN1 | |
| SCHEMBL4266132 | 0.86 | FOLH1 (0.63) | THRATHRBFOLH1PTGDR2MEN1 | |
| SCHEMBL8167328 | 0.85 | MEN1 (0.52) | THRATHRBFOLH1PTGDR2MEN1 | |
| SCHEMBL8175838 | 0.85 | PTGER4 (0.47) | THRATHRBFOLH1PTGDR2MEN1 | |
| SCHEMBL8165192 | 0.84 | MEN1 (0.53) | THRATHRBFOLH1PTGDR2MEN1 | |
| SCHEMBL8175155 | 0.84 | THRA (0.53) | THRATHRBFOLH1PTGDR2MEN1 | |
| SCHEMBL13952371 | 0.84 | PTGER4 (0.48) | THRATHRBFOLH1PTGDR2MEN1 | |
| SCHEMBL8179717 | 0.83 | PTGER4 (0.49) | THRATHRBFOLH1PTGDR2MEN1 | |
| SCHEMBL8175849 | 0.82 | PTGER4 (0.49) | THRATHRBFOLH1PTGDR2PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100867-A2 | NOVEL INHIBITORS HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2008-08-21 | — | — | WO | disclosed |