Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL816890 | 0.89 | KHK (0.50) | KHK | |
| SCHEMBL27140897 | 0.89 | KDM1A (0.51) | KDM1AMAOAMAOBKHKALDH1A1 | |
| SCHEMBL818902 | 0.89 | KDM1A (0.51) | KDM1AMAOAMAOBKHKALDH1A1 | |
| SCHEMBL20015683 | 0.89 | KDM1A (0.51) | KDM1AMAOAMAOBKHKALDH1A1 | |
| Hydrochloric Acid SCHEMBL7469111 | 0.87 | KDM1A (0.50) | KDM1AMAOAMAOBKHKALDH1A1 | |
| Hydrochloric Acid SCHEMBL27154699 | 0.87 | KDM1A (0.50) | KDM1AMAOAMAOBKHKALDH1A1 | |
| Hydrochloric Acid SCHEMBL7469122 | 0.87 | KDM1A (0.50) | KDM1AMAOAMAOBKHKALDH1A1 | |
| SCHEMBL20015401 | 0.82 | MAOB (0.46) | MAOAMAOB | |
| SCHEMBL8074183 | 0.81 | SLC18A3 (0.41) | KDM1AMAOAMAOBLMNA | |
| SCHEMBL9970115 | 0.80 | CYP11B1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104169258-A | Novel heterocyclic carboxamides as modulators of kinase activity | MERCK PATENT GMBH | 2014-11-26 | — | — | CN | disclosed |
| CN-101506203-B | 2- (pyrazin-2-yl) -thiazole and 2- (1h-pyraz0l-3-yl) -thiazole derivatives as well as related compounds as stearoyl-coa desaturase (scd) inhibitors for the treatment of metabolic, cardiovascular and other syndromes | NOVARTIS AG | 2013-10-16 | — | — | CN | disclosed |
| CN-101228138-B | Neurotherapeutic azole compounds | SK HOLDINGS CO LTD | 2012-11-21 | — | — | CN | disclosed |
| US-20110275756-A1 | CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-10 | — | — | US | disclosed |
| US-20110245398-A1 | METHOD FOR PRODUCING CONJUGATED DIENE POLYMER COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-10-06 | — | — | US | disclosed |
| CN-101506203-A | 2- (pyrazin-2-yl) -thiazole and 2- (1h-pyraz0l-3-yl) -thiazole derivatives as well as related compounds as stearoyl-coa desaturase (scd) inhibitors for the treatment of metabolic, cardiovascular and o | NOVARTIS AG (CH) | 2009-08-12 | — | — | CN | disclosed |
| CN-101228138-A | Neurotherapeutic azole compounds | SK HOLDINGS CO LTD (KR) | 2008-07-23 | — | — | CN | disclosed |