Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817574 | 0.91 | TSHR (0.46) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL818249 | 0.91 | TSHR (0.44) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL818897 | 0.90 | ALDH1A1 (0.48) | ALDH1A1LMNATSHRESR1TP53 | |
| SCHEMBL817658 | 0.87 | CA12 (0.40) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL818213 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNATSHRTDP1CYP3A4 | |
| SCHEMBL817521 | 0.73 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL819220 | 0.70 | ALDH1A1 (0.42) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL818618 | 0.68 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL3662482 | 0.68 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL818362 | 0.68 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRTDP1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |