Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.89 |
| ▸ | NPC1 | O15118 | 6/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 1/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | FPR2 | P25090 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | NAMPT | P43490 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CASR | P41180 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5427744 | 0.94 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2HIF1AMAOB | |
| SCHEMBL17916794 | 0.92 | SMN1; SMN2 (0.88) | RAB9ANPC1SMN1; SMN2HIF1AHDAC1 | |
| SCHEMBL17831080 | 0.92 | NPC1 (0.84) | RAB9ANPC1SMN1; SMN2HIF1AMAOB | |
| SCHEMBL23747763 | 0.91 | NPC1 (0.78) | RAB9ANPC1SMN1; SMN2HIF1AMAOB | |
| SCHEMBL26097972 | 0.91 | NPC1 (0.80) | RAB9ANPC1SMN1; SMN2HIF1AMAOB | |
| SCHEMBL26101164 | 0.89 | NPC1 (0.80) | RAB9ANPC1SMN1; SMN2HIF1AHDAC1 | |
| SCHEMBL23747796 | 0.89 | NPC1 (0.74) | RAB9ANPC1SMN1; SMN2HIF1AMAOB | |
| SCHEMBL16562080 | 0.87 | NPC1 (0.77) | RAB9ANPC1SMN1; SMN2HIF1AMEN1 | |
| SCHEMBL23728269 | 0.87 | POLB (0.81) | RAB9ANPC1SMN1; SMN2HIF1AHDAC1 | |
| SCHEMBL23728200 | 0.87 | NPC1 (0.77) | RAB9ANPC1SMN1; SMN2HIF1AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664704-B | A kind of synthetic N, the method for N '-disubstituted urea | NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-05-18 | — | — | CN | disclosed |
| CN-105481723-A | Preparation method for alkyl/benzyl/aryl urea compounds through heterogeneous-phase catalysis | UNIV CHINA AGRICULTURAL | 2016-04-13 | — | — | CN | disclosed |
| CN-103664704-A | Method for synthesizing N,N'-disubstituent urea | UNIV NANJING SCIENCE & TECH | 2014-03-26 | — | — | CN | disclosed |
| US-6124288-A | Xanthines and their therapeutic use | DARWIN DISCOVERY, LTD. (GB) | 2000-09-26 | — | — | US | disclosed |
| US-5821366-A | Xanthines and their therapeutic use | CHIROSCIENCE LIMITED (GB) | 1998-10-13 | — | — | US | disclosed |