SCHEMBL8175504

SCHEMBL8175504

COC1(C(O[SiH](c2ccccc2)c2ccccc2)C(C)(C)C)COC(OC(C)=O)C1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8175538 0.86 TSHR (0.31) TSHRKMT2A
SCHEMBL8174391 0.84
SCHEMBL8174709 0.74
SCHEMBL8612053 0.70 BCHE (0.32)
SCHEMBL1130830 0.70 BCHE (0.32)
SCHEMBL9196415 0.69 ALDH1A1 (0.30)
SCHEMBL8175539 0.67 SMYD2 (0.37) TSHRKMT2A
SCHEMBL9404718 0.66
SCHEMBL1417545 0.66 MEN1 (0.32) TSHRKMT2A
SCHEMBL187155 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6072051-A VIRICIDE AGAINST HEPATITIS B VIRUS WITH LOW TOXICITY CHONG KUN DANG CORP. (KR) 2000-06-06 US disclosed
EP-0882058-A1 NOVEL NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THE SAME CHONG KUN DANG CORP (KR) 1998-12-09 EP disclosed
WO-1997016456-A1 NOVEL NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THE SAME CHONG KUN DANG CORP. (KR) 1997-05-09 WO disclosed