Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.54 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | PTPRF | P10586 | 1/20 | 0.48 |
| ▸ | PTPRA | P18433 | 1/20 | 0.48 |
| ▸ | PTPRB | P23467 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.48 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176265 | 0.93 | PTPN7 (0.48) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL7820324 | 0.93 | PTPN1 (0.53) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL7819761 | 0.87 | PTPN1 (0.49) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL7825407 | 0.84 | PTPN1 (0.56) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL7825641 | 0.83 | PTPN1 (0.66) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL5988088 | 0.83 | PTPN1 (0.53) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL7814410 | 0.83 | PTPN1 (0.49) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL8473209 | 0.82 | PTPN1 (0.55) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL21164781 | 0.82 | PTPN7 (0.59) | PTPN1PTPN12ACACAPTPN7ALOX15 | |
| SCHEMBL8181990 | 0.81 | SMN1; SMN2 (0.43) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110962-A | FOR TREATING INSULIN RESISTANCE, TYPE II DIABETES, HYPERGLYCEMIA, MODULATING INSULIN LEVELS IN MAMMALS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-08-29 | — | — | US | claimed |
| US-6110962-A | FOR TREATING INSULIN RESISTANCE, TYPE II DIABETES, HYPERGLYCEMIA, MODULATING INSULIN LEVELS IN MAMMALS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-08-29 | — | — | US | disclosed |