Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 14/20 | 0.55 |
| ▸ | PTPN12 | Q05209 | 2/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.52 |
| ▸ | PTPRF | P10586 | 1/20 | 0.52 |
| ▸ | PTPRA | P18433 | 1/20 | 0.52 |
| ▸ | PTPRB | P23467 | 1/20 | 0.52 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474628 | 0.87 | PTPN1 (0.45) | PTPN1PTPN12PTPRCPTPRFPTPRA | |
| SCHEMBL8175663 | 0.82 | PTPN1 (0.54) | PTPN1PTPN12PTPRCPTPRFPTPRA | |
| SCHEMBL8474403 | 0.82 | CNR1 (0.40) | PTPN1PTPN12PTPRCPTPRFPTPRA | |
| SCHEMBL7810836 | 0.81 | PTPN1 (0.73) | PTPN1PTPN12PTPRCPTPRFPTPRA | |
| SCHEMBL7820324 | 0.81 | PTPN1 (0.53) | PTPN1PTPN12PTPRCPTPRFPTPRA | |
| SCHEMBL8473014 | 0.80 | PTPN1 (0.54) | PTPN1PTPN12PTPRCPTPRFPTPRA | |
| SCHEMBL8471275 | 0.78 | PTPN1 (0.47) | PTPN1DUSP3MEN1KMT2AALDH1A1 | |
| SCHEMBL8176265 | 0.76 | PTPN7 (0.48) | PTPN1PTPN12PTPRCPTPRFPTPRA | |
| SCHEMBL7819761 | 0.75 | PTPN1 (0.49) | PTPN1PTPN12PTPRCPTPRFPTPRA | |
| SCHEMBL8471760 | 0.73 | PTPN1 (0.65) | PTPN1PTPN12PTPRCPTPRFPTPRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001867-A | HYPOGLYCEMIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-12-14 | — | — | US | claimed |
| US-6001867-A | HYPOGLYCEMIC AGENT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-12-14 | — | — | US | disclosed |