Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 8/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818718 | 0.97 | TSHR (0.47) | TSHRTDP1L3MBTL1ESR1MAPK1 | |
| SCHEMBL818266 | 0.95 | ALDH1A1 (0.49) | TSHRESR1MAPK1CYP3A4TP53 | |
| SCHEMBL817802 | 0.91 | ALDH1A1 (0.42) | TSHRTDP1L3MBTL1ESR1MAPK1 | |
| SCHEMBL818392 | 0.85 | CA12 (0.42) | TSHRTDP1ESR1CYP3A4LMNA | |
| SCHEMBL817791 | 0.80 | ALDH1A1 (0.53) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL9863236 | 0.79 | TSHR (0.55) | TSHRTDP1L3MBTL1ESR1MAPK1 | |
| SCHEMBL819114 | 0.77 | ALDH1A1 (0.44) | TSHRTDP1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL817550 | 0.76 | TSHR (0.45) | TSHRTDP1L3MBTL1ESR1MAPK1 | |
| SCHEMBL24245273 | 0.76 | TSHR (0.51) | TSHRTDP1L3MBTL1ESR1MAPK1 | |
| SCHEMBL818348 | 0.76 | TSHR (0.51) | TSHRTDP1L3MBTL1ESR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |