Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818502 | 0.84 | KDM4E (0.39) | TSHRALDH1A1RAB9AHSD17B10HTT | |
| SCHEMBL819412 | 0.82 | ALDH1A1 (0.38) | TSHRALDH1A1NPC1RAB9ACHRM2 | |
| SCHEMBL818317 | 0.80 | ALDH1A1 (0.49) | TSHRALDH1A1HSD17B10CYP3A4LMNA | |
| SCHEMBL818057 | 0.79 | ALDH1A1 (0.41) | TSHRALDH1A1NPC1RAB9ACHRM2 | |
| SCHEMBL818880 | 0.78 | TSHR (0.42) | TSHRALDH1A1NPC1RAB9ACHRM2 | |
| SCHEMBL818661 | 0.78 | ALDH1A1 (0.35) | TSHRALDH1A1NPC1RAB9AHSD17B10 | |
| SCHEMBL816941 | 0.78 | ALDH1A1 (0.43) | TSHRALDH1A1NPC1RAB9ACHRM2 | |
| SCHEMBL818426 | 0.77 | ALDH1A1 (0.43) | TSHRALDH1A1NPC1RAB9AHSD17B10 | |
| SCHEMBL818845 | 0.76 | TSHR (0.49) | TSHRALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL818805 | 0.69 | ALDH1A1 (0.45) | TSHRALDH1A1NPC1RAB9ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |