Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 8/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MC5R | P33032 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176163 | 1.00 | GHSR (0.70) | GHSRALDH1A1MAPTMC4RMC5R | |
| SCHEMBL6325114 | 0.90 | GHSR (0.69) | GHSRMC4RMC5RMC3R | |
| SCHEMBL6325120 | 0.90 | GHSR (0.69) | GHSRMC4RMC5RMC3R | |
| SCHEMBL8169749 | 0.87 | GHSR (0.59) | GHSR | |
| SCHEMBL8169746 | 0.87 | GHSR (0.59) | GHSR | |
| SCHEMBL8227229 | 0.86 | GHSR (0.65) | GHSRALDH1A1MAPT | |
| SCHEMBL3268360 | 0.86 | GHSR (0.65) | GHSRALDH1A1MAPT | |
| SCHEMBL13307558 | 0.86 | GHSR (0.65) | GHSRALDH1A1MAPT | |
| SCHEMBL3268355 | 0.86 | GHSR (0.65) | GHSRALDH1A1MAPT | |
| SCHEMBL8174025 | 0.84 | GHSR (0.71) | GHSRMC4RMC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127341-A | AMINOMETHYL-N-(1-((2-(2-THIENYL)-1-(1-CARBAMOYL-5 -AMINOPENTYLCARBAMOYL)ETHYL)-N-METHYLCARBAMOYL)-2-(2 -NAPTHYL)ETHYL)BENZAMIDE, FOR EXAMPLE; ADMINISTERING TO STIMULATE GROWTH, MILK OR WOOL PRODUCTION IN ANIMALS | NOVO NORDISK A/S (DK) | 2000-10-03 | — | — | US | claimed |
| US-6127341-A | AMINOMETHYL-N-(1-((2-(2-THIENYL)-1-(1-CARBAMOYL-5 -AMINOPENTYLCARBAMOYL)ETHYL)-N-METHYLCARBAMOYL)-2-(2 -NAPTHYL)ETHYL)BENZAMIDE, FOR EXAMPLE; ADMINISTERING TO STIMULATE GROWTH, MILK OR WOOL PRODUCTION IN ANIMALS | NOVO NORDISK A/S (DK) | 2000-10-03 | — | — | US | disclosed |
| EP-1005484-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 2000-06-07 | — | — | EP | disclosed |
| WO-1998058950-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-12-30 | — | — | WO | disclosed |