SCHEMBL8176306

SCHEMBL8176306

[CH2]C1C/C=C\CCCCCCC1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8189937 1.00 ALDH1A1 (0.34) ALDH1A1ALOX15
SCHEMBL8186543 1.00 ALDH1A1 (0.34) ALDH1A1ALOX15
SCHEMBL8186541 1.00 ALDH1A1 (0.34) ALDH1A1ALOX15
SCHEMBL8189935 1.00 ALDH1A1 (0.34) ALDH1A1ALOX15
SCHEMBL8176310 1.00 ALDH1A1 (0.34) ALDH1A1ALOX15
SCHEMBL7994879 0.97
SCHEMBL7994814 0.90
SCHEMBL8185707 0.84
SCHEMBL8185854 0.84
SCHEMBL8184823 0.82 ALDH1A1 (0.31) ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6140338-A FOR TREATING ACUTE INFLAMMATORY DISEASES, CHRONIC INFLAMMATORY DISEASES, ACQUIRED IMMUNE DEFICIENCY SYNDROME, CANCER, ISCHEMIC REFLOW DISORDER AND/OR ARTERIOSCLEROSIS BANYU PHARMACEUTICAL, CO., LTD. (JP) 2000-10-31 US disclosed
EP-0916668-A1 CHEMOKINE RECEPTOR ANTAGONISTS BANYU PHARMACEUTICAL CO., LTD. (JP) 1999-05-19 EP disclosed