Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | F9 | P00740 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8168631 | 0.85 | F9 (0.49) | CYP1A2CYP2C9CYP2C19CYP3A4POLB | |
| SCHEMBL8167427 | 0.84 | SMN1; SMN2 (0.47) | CYP1A2CYP2C9CYP2C19CYP3A4POLB | |
| SCHEMBL8176394 | 0.83 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19CYP3A4POLB | |
| SCHEMBL8175262 | 0.82 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19CYP3A4POLB | |
| SCHEMBL63446 | 0.81 | CYP1A2 (0.62) | CYP1A2CYP2C9CYP2C19CYP3A4POLB | |
| SCHEMBL8175811 | 0.80 | HSP90AA1 (0.39) | CYP1A2CYP2C9CYP2C19CYP3A4POLB | |
| SCHEMBL20556372 | 0.78 | MAPT (0.52) | MAPTMYCKDM4EALOX15TSHR | |
| SCHEMBL8490965 | 0.76 | F9 (0.42) | MAPTSMN1; SMN2HTTHSP90AA1KDM4E | |
| SCHEMBL5869031 | 0.76 | TP53 (0.64) | CYP1A2CYP2C9CYP2C19CYP3A4POLB | |
| SCHEMBL20556408 | 0.76 | MAPT (0.44) | POLBMAPTMYCKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834183-B2 | Process for producing N-(hetero)aryl-substituted nitrogen-containing heteroaryl compound | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2010-11-16 | — | — | US | disclosed |
| US-7834183-B2 | Process for producing N-(hetero)aryl-substituted nitrogen-containing heteroaryl compound | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2010-11-16 | — | — | US | disclosed |
| US-20070135633-A1 | Process for producing N-(hetero)aryl-substituted nitrogen-containing heteroaryl compound | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2007-06-14 | — | — | US | disclosed |
| US-20070135633-A1 | Process for producing N-(hetero)aryl-substituted nitrogen-containing heteroaryl compound | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2007-06-14 | — | — | US | disclosed |
| EP-1795529-A2 | Process for producing N-(Hetero)Aryl-substituted nitrogen-containing heteroaryl compound | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-6048984-A | HERBICIDES AND ANTIGROWTH AGENTS | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2000-04-11 | — | — | US | disclosed |
| US-5977376-A | Herbicidal 2-benzoylcyclohexane-1,3-diones and related compounds | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-11-02 | — | — | US | disclosed |
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |
| WO-1999003845-A1 | 2-BENZOYLCYCLOHEXANE-1,3-DIONE DERIVATIVES AS HERBICIDES AND INTERMEDIATES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135633-A1 | Process for producing N-(hetero)aryl-substituted nitrogen-containing heteroaryl compound | PARG, PARN, ASNS | CYP1A2 215/4885CYP2C9 256/4885CYP2C19 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.