Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 3/20 | 0.40 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8180740 | 0.85 | MAPK10 (0.43) | CYP1A2CYP2C9CYP2C19POLBNOTUM | |
| SCHEMBL8526165 | 0.82 | LRRK2 (0.38) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL8176397 | 0.82 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL8168631 | 0.81 | F9 (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL8183594 | 0.81 | MAPK10 (0.37) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL8525756 | 0.81 | MAPT (0.39) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL10088436 | 0.80 | NOTUM (0.46) | NOTUMKDM4EMAPTCFTRMYC | |
| SCHEMBL8176394 | 0.79 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL8177966 | 0.78 | MAPT (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL8181128 | 0.78 | HSD11B1 (0.40) | CYP1A2CYP3A4CYP2C9CYP2C19NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048984-A | HERBICIDES AND ANTIGROWTH AGENTS | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2000-04-11 | — | — | US | disclosed |
| US-5977376-A | Herbicidal 2-benzoylcyclohexane-1,3-diones and related compounds | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-11-02 | — | — | US | disclosed |
| WO-1999003845-A1 | 2-BENZOYLCYCLOHEXANE-1,3-DIONE DERIVATIVES AS HERBICIDES AND INTERMEDIATES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |