Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLM | Q9NP87 | 2/20 | 0.64 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.64 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.64 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.64 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | F7 | P08709 | 3/20 | 0.50 |
| ▸ | F3 | P13726 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.50 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.50 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577818 | 0.92 | POLM (0.59) | POLMPOLKPOLLPOLHMAPT | |
| SCHEMBL9179143 | 0.92 | POLM (0.59) | POLMPOLKPOLLPOLHMAPT | |
| SCHEMBL28309018 | 0.92 | POLM (0.59) | POLMPOLKPOLLPOLHMAPT | |
| SCHEMBL22261900 | 0.91 | POLM (0.62) | POLMPOLKPOLLPOLHHTR2A | |
| SCHEMBL30666136 | 0.88 | POLM (0.67) | POLMPOLKPOLLPOLHHTR2A | |
| SCHEMBL8176584 | 0.86 | POLM (0.57) | POLMPOLKPOLLPOLHF7 | |
| SCHEMBL11765126 | 0.86 | POLM (0.62) | POLMPOLKPOLLPOLHMAPT | |
| SCHEMBL11420384 | 0.84 | POLM (0.48) | POLMPOLKPOLLPOLHMMP2 | |
| SCHEMBL11419979 | 0.83 | KMT2A (0.46) | POLMPOLKPOLLPOLHMMP2 | |
| SCHEMBL20739827 | 0.83 | POLM (0.62) | POLMPOLKPOLLPOLHHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000009139-A2 | METHODS FOR PROMOTING SURVIVAL OF MYELIN PRODUCING CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-02-24 | — | — | WO | disclosed |