Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.58 |
| ▸ | MYC | P01106 | 1/20 | 0.58 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.58 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568099 | 0.83 | SOAT2 (0.67) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL8180547 | 0.83 | SOAT2 (0.52) | SOAT2MYCSOAT1MAP2K3CA1 | |
| Hydrochloric Acid SCHEMBL7568093 | 0.82 | SOAT2 (0.66) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL7566056 | 0.82 | SOAT2 (0.60) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL7569954 | 0.82 | SOAT2 (0.64) | SOAT2MYCSOAT1MAP2K3 | |
| Hydrochloric Acid SCHEMBL7571960 | 0.81 | SOAT2 (0.63) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL7567765 | 0.79 | SOAT2 (0.75) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL7566794 | 0.78 | SOAT2 (0.73) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL8168466 | 0.77 | SOAT2 (0.66) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL7567505 | 0.77 | SOAT2 (0.78) | SOAT2MYCSOAT1MAP2K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093744-A | USE AS CEREBROVASCULAR AGENTS IN DISEASES SUCH AS STROKE, PERIPHERAL VASCULAR DISEASE, RESTENOSIS, AND AS AGENTS FOR REGULATING PLASMA CHOLESTEROL CONCENTRATIONS, FOR TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 2000-07-25 | — | — | US | disclosed |
| WO-1997044314-A1 | N-ACYL SULFAMIC ACID ESTERS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1997-11-27 | — | — | WO | disclosed |