Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8186780 | 0.87 | DHODH (0.33) | CYP4F2CYP4A11NPC1ADORA3KDM4E | |
| SCHEMBL8190377 | 0.84 | IGF1R (0.33) | ADRA1AADRA1B | |
| SCHEMBL8193219 | 0.73 | KDM4E (0.32) | KDM4EALDH1A1 | |
| SCHEMBL22996403 | 0.66 | BRD4 (0.33) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL2160110 | 0.60 | CYP4F2 (0.51) | CYP4F2CYP4A11ALDH1A1HPGDHSD17B10 | |
| SCHEMBL23900661 | 0.59 | CA12 (0.41) | MMP1MMP2MMP9MMP12NPC1 | |
| SCHEMBL8187093 | 0.59 | PDE4A (0.37) | CYP4F2CYP4A11NPC1RAB9AALDH1A1 | |
| SCHEMBL3977225 | 0.58 | CYP4A11 (1.00) | CYP4F2CYP4A11NPC1RAB9AALDH1A1 | |
| SCHEMBL10438609 | 0.57 | KDM4E (0.36) | KDM4ENPSR1 | |
| SCHEMBL29113516 | 0.56 | GPR17 (0.48) | KDM4EALDH1A1HPGDHSD17B10TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057330-A | USEFUL FOR THE PREVENTION AND TREATMENT OF A RESPIRATORY DISEASES REPRESENTED BY ASTHMA | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-05-02 | — | — | US | disclosed |
| US-5942515-A | RESPIRATORY SYSTEM DISORDERS | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1999-08-24 | — | — | US | disclosed |