Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RPA1 | P27694 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22996541 | 0.81 | SMN1; SMN2 (0.36) | BRD4SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL8177100 | 0.79 | GAA (0.33) | BRD4KDM4EGAA | |
| SCHEMBL8176750 | 0.75 | GAA (0.43) | BRD4KDM4EALDH1A1GAA | |
| SCHEMBL23702701 | 0.74 | KDM4E (0.35) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8205389 | 0.72 | GAA (0.36) | KDM4EALDH1A1GAA | |
| SCHEMBL8193219 | 0.70 | KDM4E (0.32) | KDM4EALDH1A1GAA | |
| SCHEMBL8186780 | 0.69 | DHODH (0.33) | KDM4EALDH1A1HPGDGAA | |
| SCHEMBL8177653 | 0.66 | CYP4F2 (0.39) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8190377 | 0.66 | IGF1R (0.33) | — | |
| SCHEMBL8186146 | 0.66 | DAO (0.36) | SMN1; SMN2KDM4EHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021027503-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND INTERMEDIATE AND USE THEREOF | 罗欣药业(上海)有限公司 | 2021-02-18 | — | — | WO | disclosed |