Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8178771 | 0.86 | TDP1 (0.62) | TDP1L3MBTL1MEN1LMNATSHR | |
| SCHEMBL30602599 | 0.84 | TDP1 (0.67) | TDP1L3MBTL1TSHRGPR84HDAC8 | |
| SCHEMBL12193888 | 0.84 | TDP1 (0.67) | TDP1L3MBTL1TSHRGPR84HDAC8 | |
| SCHEMBL9395271 | 0.82 | TDP1 (0.53) | TDP1L3MBTL1MEN1LMNATSHR | |
| SCHEMBL8189201 | 0.81 | TDP1 (0.66) | TDP1L3MBTL1MEN1LMNATSHR | |
| SCHEMBL15955998 | 0.79 | TDP1 (0.67) | TDP1L3MBTL1TSHRGPR84HDAC8 | |
| SCHEMBL9219707 | 0.78 | TDP1 (1.00) | TDP1L3MBTL1ACHE | |
| SCHEMBL5093425 | 0.78 | TDP1 (1.00) | TDP1L3MBTL1ACHE | |
| SCHEMBL31035964 | 0.78 | TDP1 (1.00) | TDP1L3MBTL1ACHE | |
| SCHEMBL29263641 | 0.78 | TDP1 (1.00) | TDP1L3MBTL1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127529-A | FORMS STABLE CHELATE COMPOUND USEFUL FOR LABELING BIOLOGICAL TARGETING COMPOUND RESIDUE | WALLAC OY (FI) | 2000-10-03 | — | — | US | disclosed |
| EP-0298939-B1 | Metal-chelating 2,6-disubstituted pyridine compounds and their use | WALLAC OY (FI) | 1994-01-12 | — | — | EP | disclosed |
| EP-0378652-A1 | OLIGONUCLEOTIDE HYBRIDIZATION PROBES AND MEANS FOR THE SYNTHESIS OF THE MOST PREFERRED PROBES | WALLAC OY (FI) | 1990-07-25 | — | — | EP | disclosed |
| WO-1990000622-A1 | OLIGONUCLEOTIDE HYBRIDIZATION PROBES AND MEANS FOR THE SYNTHESIS OF THE MOST PREFERRED PROBES | WALLAC OY (FI) | 1990-01-25 | — | — | WO | disclosed |
| EP-0298939-A1 | Metal-chelating 2,6-disubstituted pyridine compounds and their use | WALLAC OY (FI) | 1989-01-11 | — | — | EP | disclosed |