Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 1/20 | 1.00 |
| ▸ | MYC | P01106 | 3/20 | 0.73 |
| ▸ | MAX | P61244 | 2/20 | 0.73 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.68 |
| ▸ | IL1RN | P18510 | 1/20 | 0.65 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.65 |
| ▸ | PIM1 | P11309 | 3/20 | 0.64 |
| ▸ | GSK3B | P49841 | 2/20 | 0.64 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.64 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.64 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | CDC7 | O00311 | 1/20 | 0.64 |
| ▸ | PLK4 | O00444 | 1/20 | 0.64 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.64 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.64 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.64 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.64 |
| ▸ | PRKCG | P05129 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8178911 | 1.00 | PTP4A3 (1.00) | PTP4A3MYCMAXCISD1IL1RN | |
| SCHEMBL6448804 | 0.88 | PTP4A3 (0.78) | PTP4A3MYCMAXCISD1PIM1 | |
| SCHEMBL6450013 | 0.88 | PTP4A3 (0.78) | PTP4A3MYCMAXCISD1PIM1 | |
| SCHEMBL6448803 | 0.88 | PTP4A3 (0.78) | PTP4A3MYCMAXCISD1PIM1 | |
| SCHEMBL8179904 | 0.85 | PTP4A3 (0.74) | PTP4A3MYCMAXCISD1IL1RN | |
| SCHEMBL8179901 | 0.85 | PTP4A3 (0.74) | PTP4A3MYCMAXCISD1IL1RN | |
| SCHEMBL15421744 | 0.85 | MYC (1.00) | PTP4A3MYCMAXCISD1IL1RN | |
| SCHEMBL15421743 | 0.85 | MYC (1.00) | PTP4A3MYCMAXCISD1IL1RN | |
| SCHEMBL15421742 | 0.85 | MYC (1.00) | PTP4A3MYCMAXCISD1IL1RN | |
| SCHEMBL6413629 | 0.84 | PTP4A3 (0.73) | PTP4A3MYCMAXCISD1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018748-A1 | RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |