Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.82 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.82 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13660067 | 0.93 | KCNH2 (0.82) | KCNH2CHRNA7CHRNA3 | |
| SCHEMBL1854943 | 0.90 | KCNH2 (1.00) | KCNH2CHRNA7CHRNA3 | |
| Hydrochloric Acid SCHEMBL1863445 | 0.89 | KCNH2 (0.98) | KCNH2CHRNA7CHRNA3 | |
| SCHEMBL2089789 | 0.89 | KCNH2 (0.98) | KCNH2CHRNA7CHRNA3 | |
| SCHEMBL8179059 | 0.89 | KCNH2 (0.69) | KCNH2CHRNA7CHRNA3 | |
| Hydrochloric Acid SCHEMBL4085058 | 0.89 | KCNH2 (0.97) | KCNH2CHRNA7CHRNA3 | |
| SCHEMBL8188721 | 0.87 | KCNH2 (0.79) | KCNH2CHRNA7CHRNA3 | |
| SCHEMBL8193403 | 0.87 | KCNH2 (0.81) | KCNH2CHRNA7CHRNA3 | |
| SCHEMBL8179039 | 0.84 | KCNH2 (0.80) | KCNH2CHRNA7CHRNA3 | |
| SCHEMBL2055694 | 0.83 | CHRNA7 (0.59) | KCNH2CHRNA7CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009091813-A1 | COMPOUNDS USEFUL AS ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS | WYETH (US) | 2009-07-23 | — | — | WO | disclosed |
| US-20090181952-A1 | COMPOUNDS USEFUL AS ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS | WYETH (US) | 2009-07-16 | — | — | US | disclosed |
| US-20090181952-A1 | COMPOUNDS USEFUL AS ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS | WYETH (US) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181952-A1 | COMPOUNDS USEFUL AS ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS | CHRNA7, CHRNA2, CHRNA6 | KCNH2 732/4885CHRNA7 1/4885CHRNA3 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.