SCHEMBL817946

SCHEMBL817946

C=C(C)c1ccccc1C(C)C1CCCNC1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 10/20 0.43
SLC6A4 P31645 10/20 0.43
SLC6A3 Q01959 4/20 0.37
KCNH2 Q12809 2/20 0.37
CYP2D6 P10635 1/20 0.37
CCR8 P51685 1/20 0.37
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA4 P43681 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL817591 0.92 SLC6A2 (0.45) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL818794 0.83 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
Hydrochloric Acid SCHEMBL29202362 0.77 SLC6A2 (0.48) SLC6A2SLC6A4SLC6A3CCR8
SCHEMBL817514 0.77 SLC6A2 (0.36) SLC6A2SLC6A4SLC6A3CCR8
SCHEMBL816986 0.75 ADRA2A (0.36) SLC6A2SLC6A4SLC6A3KCNH2ADRA2A
SCHEMBL10514170 0.75 SLC6A2 (0.51) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL19121854 0.73 SLC6A2 (0.44) SLC6A2SLC6A4SLC6A3
SCHEMBL817794 0.71 HTR2A (0.43) SLC6A2SLC6A4SLC6A3KCNH2CYP2D6
SCHEMBL23848197 0.69 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3CYP2D6CHRNB4
SCHEMBL818681 0.69 EED (0.50) SLC6A2SLC6A4SLC6A3CHRNB2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110275756-A1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-10 US disclosed