Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.82 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.76 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.76 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.76 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.76 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.76 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.76 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.76 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.76 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.76 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.76 |
| ▸ | CNR1 | P21554 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8172080 | 0.98 | L3MBTL1 (0.84) | L3MBTL1HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL27291378 | 0.92 | L3MBTL1 (0.96) | L3MBTL1HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL16438801 | 0.87 | L3MBTL1 (0.75) | L3MBTL1HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL23055044 | 0.86 | HDAC1 (1.00) | L3MBTL1HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL12215287 | 0.86 | L3MBTL1 (0.84) | L3MBTL1HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL30444656 | 0.86 | L3MBTL1 (0.84) | L3MBTL1HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL30021084 | 0.86 | L3MBTL1 (0.84) | L3MBTL1HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL10647695 | 0.86 | L3MBTL1 (0.84) | L3MBTL1HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL9077076 | 0.86 | L3MBTL1 (0.84) | L3MBTL1HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL27909129 | 0.86 | L3MBTL1 (0.84) | L3MBTL1HDAC1HDAC8HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478954-B1 | Serotonin 5HT1A and 5HT1D agonists | MERRELL PHARMA INC (US) | 2000-10-18 | — | — | EP | disclosed |
| US-5559143-A | Serotonin 5HT1A agonistic method | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-24 | — | — | US | disclosed |
| US-5387604-A | 1,4 benzodioxin derivatives and their use as serotonin 5HT1A agonists | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-02-07 | — | — | US | disclosed |
| US-5189179-A | SEROTONIN 5HT1A AGONISTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0478954-A1 | Serotonin 5HT1A and 5HT1D antagonists | MERRELL PHARMACEUTICALS INC. (US) | 1992-04-08 | — | — | EP | disclosed |